New publication release (2017-2023):

​

2023

Alshebremi M, Tomchuck SL, Myers JT, Kingsley DT, Eid S, Abiff M, Bonner M, Saab ST, Choi SH, Huang AY. Funcational tumor cell-intrinsic STING, not host STING, drives local and systemic antitumor immunity and therapy efficacy following cryoablation. J. ImmunoTherapy Cancer. 2023. 11:e006608. doi:10.1136/jitc-2022-006608 (Read).

​

Roche V, Sandoval V, Senders Z, Lyons J, Myers J, Ribeiro SP, Sekaly RP, Kim J, Huang AY, Zhang M. Carbohydrate ligand engagement with CD11b enhances differentiation of tumor-associated myeloid cells for immunotherapy of solid cancers. J. ImmunoTherapy Cancer. 2023. 11:e006205. doi: 10.1136/jitc-2022-006205 (Read).

​

Bhatia S, Pappo AS, Acquazzino M, Allen-Thoades WA, Barnett M, Borinstein SC, Casey R, Choo S, Chugh R, Dinner S, Ermoian R, Fair D, Federman N, Folbrecht J, Gandhi S, Germann J, Goldsby R, Hayashi R, Huang AY, Huang MS, Jacobs LA, Lee-Miller C, Link MP, Livingston JA, Lustberg M, Malogolowkin M, Oeffinger KC, Pratilas CA, Reed D, Skiles J, von Mehren M, Yeager N, Montgomery S, Hang L. Adolescent and Young Adult (AYA Oncology, Version 2.2024, NCCN Clinical Practice Guidelines in Oncology. J. Natl. Compr. Canc. Netw. 2023. 21(8):851-880. doi:10.6004/jnccn.2023.0040 (Read).

​

Mayca Pozo F, Geng X, Miyago M, Amin AL, Huang AY, Zhang Y. MYO10 regulates genome stability and cancer inflammation through mediating mitosis. Cell Reports. 2023, 42(5): 112531. (Read)

​

Wong D, Fritz C, Feinberg D, Huang A, Parameswaran R. p35 is a crucial player in NK cell cytotoxicity and TGF-beta mediated NK cell dysfunction. Cancer Research Communications. 2023, 3(5): 793-806. (Read)

​

Daunov K, Daunov M, Koskoff K, Gan H, Davies S, Farrell M, Hadley W, Baffa A, Giesel J, Egler R, Huang AY, Letterio JJ, Lee RT. Are national cancer institute cancer centers providing adolescent and younng adults with cancer focused clinical services? - A national survey. JNCCN 2023, 21(5): 487-495.

​

2022

VanHeyst KA, Choi SH, Kingsley DT, Huang, AY. Ectopic tumor VCAM-1 expression in cancer metastasis and therapy resistance. Cells. 2022, 11, 3922. (Read)

​

Nayak L, Sweet DR, Thomas A, Lapping SD, Kalikasingh K, Madera A, Vinayachandran V., Padmanabhan R, Vasudevan NT, Myers JT, Huang AY, Schmaier A, Mackman N, Liao X, Maiseyeu A, Jain MK. A targetable pathway in neutrophils mitigates both arterial and venous thrombosis. Sci. Transl. Med. 2022, 14(660):eabj7465 (Read).

​

Choi SH, Huang AY, Letterio JJ, Kim BG. Smad4-deficient T cells promote colitis-associated colon cancer via an IFN-g-dependent suppression of 15-hyroxyprostaglandin dehydrogenase. Front. Immunol. 2022, 13:932412 (Read)

​

Kim BG, Choi SH, Letterio JJ, Song JY, Huang AY. Overexpression of VEGF in the MOPC 315 Plasmacytoma induces tumor immunity in mice. Int. J. Mol. Sci. 2022, 23(9):5235 (Read).

​

2021

DO JS, Zwick D, Kenyon JD, Zhong F, Askew D, Huang AY, Van't Hof W, Finney M, Laughlin MJ. Mesenchymal stromal cell mitochondrial transfer to human induced T-regulatory cells mediates FOXP3 stability. Sci. Rep. 2021, 11(1):10676 (Read).

​

Wang L, Yu S, Chen KY, Liu C, Che D, Amadella A, Myers J, Askew D, Chan R, Huang AY, Maillard IP, Huang D, Ivanov I, Xin W, Zhou L. Notch-regulaed dendritic cells restrain inflammation-associated colorectal carcinogenesis. Cancer Immunol. Res. 2021, 9(3): 348-361 (Read).

​

2020

De Santis S, Verna G, Serino G, Armentano R, Cavalcanti E, Liso M, Dicarlo M, Coletta S, Mastronardi M, Lippolis T, Tafaro A, Santino A, Pinto A, Campiglia P, Huang AY, Cominelli F, Pizzarro TT, Chieppa M. Winnie-APC Min/+ Mice: a spontaneous model of colitis-associated colorectal cancer combining genetics and inflammation. Int. J. Mol. Sci 2020, 21(8):2972 (Read).

​

2019

Wang SC, Yang KD, Lin CY, Huang AY, Hsiao CC, Lin MT, Tsai YG. Intravenous immunoglobulin therapy enhances suppressive regulatory T cells and decreases innate lymphoid cells in children with immune thrombocytopenia. Peds. Blood & Cancer 2019, e28075 (Read).

​

Evans TA, Bury LA, Huang AY, Sabo SL. Spatio-temporal dynamics of neocortical presynaptic terminal development using multi-photon imaging of the corpus callosum in vivo. Nature Sci. Report 2019. 9(1): 14028. (Read).

​

Dorand RD, Benson BL, Huang LF, Petrosiute A, Huang AY. Insights from dynamic neuro-immune imaging on murine immune responses to CNS damage. Front. Neurosci. 2019. 13:737. (Read)

​

Tong AA*, Forestell B*, Murphy DV, Nair A, Allen F, Myers J, Heim D, Klauschen F, Gopal A, Huang AY^, Mandl J^. Regulatory T cells differ from conventional CD4+ T cells in their recirculatory behavior and lymph node residency times. Immunol. Cell Biol. 2019. doi: 10.1111/imcb.12276. (*co-first authors; ^co-senior authors). [Read]

​

Gollamudi J, Huang AY, Stavrou EX. Physiological Roles of Leukocytes and Disorders. In: Lazarus H, Schmaier A. (Eds) Concise Guide to Hematology. Springer, Cham. pp 209-224.

​

2018

Rathkey JK, Zhao J, Liu Z, Chen Y, Yang J, Kondolf HC, Benson BL, Chirleleison SM, Huang AY, Dubyak GR, Xiao TS, Li X, Abbott DW. Chemical disruption of the pyroptotic pore-forming protein gasdermin D inhibits inflammatory cell death and sepsis. Sci. Immunol. 2018. 3(26): pii: eaat2738. [Read].

​

Qiu H, Zmina PM, Huang AY, Askew D, Bedogni B. Inhibiting Notch1 enhances immunotherapy efficacy in melanoma by preventing Notch1 dependent immune suppressive properties. Cancer Lett. 2018. 434:144-151. [Read}

​

Benson BL, Li L, Myers JT, Dorand RD, Gurkan UA, Huang AY*, Ransohoff RM. Biomimetic post-capillary venule expansions for leukocyte adhesion studies. Nature Scientific Reports 2018. 8:9328. [Read}

​

Borton AH, Benson BL, Nellson LE, Saunders A, Alaiti MA, Huang AY, Jain MK, Proweller A, Ramirez-Bergeron DL. Aryl hydrocarbone receptor nuclear translocator in vascular smooth muscle cells is required for optimal peripheral perfusion recovery. J Am Heart Assoc 2018. 7(11). pii.e009205. [Read]

​

Do J-S, Zhong F, Huang AY, van't Hof W, Finney M, Laughlin MJ. Foxp3 expression in induced T regulatory cells derived from human umbilical cord blood vs. adult peripheral blood. Bone Marrow Transplantation 2018. In press.

​

Huang AY. Cancer Moonshot: Immunotherapy has breathed new life into cancer treatment. Conquer Magazine 2018. 4(1). [Read]

​

Zhang M, Kim J, Huang AY. Optimizing tumor microenvironment for cancer immunotherapy: beta-glucan-based nanoparticles. Frontiers in Immunology 2018. doi: 10.3389/fimmu.2018.00341. [Read]

​

Metheny L, Eid S, Lingas K, Ofir R, Pinzur L, Meyerson H, Lazarus HM, Huang AY. Post-transplant intramuscular injection of PLX-R18 mesenchymal-like adherent stromal cells improves human hematopoietic engraftment in a murine transplant model. Frontiers in Medicine 2018. doi: 10.3389/fmed.2018.00037. [Read].

​

Morrow J, et al. Positively selected enhancer elements endow tumor cells with metastatic competence. Nature Medicine 2018. 24(2): 176-185. doi:10.1038/nm.4475. [Read}

​

2017

Dorand RD, Petrosiute A, Huang AY. Multifactorial regulator of tumor PD-L1 response. Transl. Cancer Research 2017. doi: 10.21037/tcr.2017.11.08. [Read]

 

Allen F, Bobanga I, Rauhe P, Barkauskas D, Teich N, Tong C, Myers J, Huang AY. CCL3 augments tumor rejection and enhances CD8+ T cell infiltration through NK and CD103+ dendritic cell recruitment via IFNg. OncoImmunology 2017. 7(3): e1393598. [Read]

 

Allen F, Myers J, Tong AA, Rauhe P, Nathle J, Eid S, Huang AY. CCL3 enhances antitumor immune priming in the tumor draining lymph node via IFNg with dependency on natural killer cells. Frontiers in Immunology 2017. 8:1390. [Read]

 

Zhang M, Chun L, Sandoval V, Graor H, Myers J, Nthale J, Rauhe P, Senders Z, Choong K, Huang AY, Kim J. Systemic administration of beta-glucan of 200 kDa modulates melanoma microenvironment and suppresses metastatic cancer. OncoImmunology 2017. 7(2): e1387347. [Read]