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Huang Laboratory at Case Western Reserve University School of Medicine

Discovering Immunity in Health & Disease. Finding Cures for Childhood Cancer.

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                                                               This page was last modified on Thursday, December 18, 2014 04:28:42 PM

                                 
Welcome to the

Huang Lab
at
Case Western Reserve University School of Medicine 
 
Principal Investigator

Alex Y. Huang, MD, PhD
Associate Professor of Pediatrics, Pathology, BME and General Medical Sciences

 
Case Western Reserve University
Angie Fowler AYA Cancer Institute
University Hospitals Case Medical Center
Rainbow Babies & Children's Hospital
Cleveland, Ohio USA


Upcoming Seminar / Conference Engagement:
  • Cancer Stem Cell Conference, Cleveland, OH, August 18, 2014
  • Dialogue on Discovery, Cleveland, OH, September 11, 2014
  • Immunology Seminar, Cleveland, OH, September 16, 2014
  • Hyundai Hope-on-Wheels, Washington DC, September 17, 2014 (Dr. Petrosiute)
  • Case Comprehensive Cancer Center Research Seminar, Cleveland, OH, September 26, 2014
  • Cancer Research Institute 22nd Annual Meeting, New York, NY October 6-8, 2014
  • 5th Gabrielle's Angel Foundation Medical Symposium & Luncheon, New York, NY October 28-29, 2014
  • AACR Tumor Immunology and Immunotherapy: A New Chapter, Orlando FL, December 1-3, 2014
  • Translational Research Cancer Center Consortium (TRC3) Meeting, Seven Springs, PA, February 18-20, 2015

Huang Lab Photos
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Focus of our laboratory:

        Regulation between immune activation and tolerance is crucial in the pathogenesis of cancer. Recent development of intravital 2-photon microscopy allows direct observation of how immune cells traffic and interact with various cells in the tumor micro-environment in real time with single-cell resolution.

       Our laboratory is interested in applying this and other classical immunological techniques to study various aspects of anti-tumor immune responses, immune – host – pathogen interaction, T cell-mediated memory immunity, and chemokine - receptor biology.  Ongoing projects include:
 
1) Investigation into factors which influence the dynamic recruitment of T cells and their interactions with tumor cells and associated antigen-presenting cells in tumor-associated micro-environment
 
2) Imaging dynamic interaction between peri-vascular APC and T cells in the CNS during induction of acute experimental autoimmune encephalomyelitis
 
3) Discovering molecular signaling mechanisms responsible for the regulation of chemokine receptor expression on naive T cells
 
4) Testing the efficacy of genetically-modified tumor vaccines in the setting of sarcomas and other childhood cancer
 
5) Developing imaging techniques to interrogate immune cell migration and interactions in tissues such as the bone marrow, lung, GI track and the skin.     

The long-term goal of our laboratory is to translate insights gained from basic investigations of in vivo immunity into rationally designed tumor vaccine and immunotherapeutic clinical trials, with a particular emphasis in the areas of pediatric sarcomas and other solid tumors.  
  

Recent Publications: (My NCBI)


Owusu-Ansah A, Choi SH, Petrosiute A, Letterio JJ, Huang AY. Triterpenoid inducers of Nrf2 signaling as potential therapeutic agents in sickle cell disease - a review. Frontiers of Medicine 2014, DOI: 10.1007/s11684-015-0375-1


Dorand RD, Barkauskas DS, Evans TA, Petrosiute A, Huang AY. Comparison of intravital thinned skull and cranial window approaches to study CNS immunobiology in the mouse cortex. Intravital 2014; 3:e29728.


Evans TA, Barkauskas DS, Myers JT, Huang AY. Intravital imaging of dynamic axonal interactions with microglia and macrophages in a mouse dorsal column crush injury. J. Vis. Exp. 2014, (93), e52228.


Ravikumar M, Sunil S, Black J, Barkauskas DS, Huang AY, Miller RH, Selkirk SM, Capadona JR. Blood-derived macrophages domoninate over resident microglia in mediating the neuroinflammatory response to implanted intracortical microelectrodes. Biomaterials. 2014; 35(28): 8049-8064..


Cavalcanti E, Vadrucci E, Delvecchio F, Addabbo F, Bettini S, Liou R, Huang AY, Pizzaro TT, Santino A, Chieppa M. Reconstituted oil bodies polyphenol mix administration efficeintly suppress dendritic cell inflammatory pathway and acute intestinal inflammation. PLoS ONE 2014; 9(2): e88898.


Evans, TA, Barkauskas, DS, Myers J, You, JQ, Hare EG, Ransohoff R, Huang AY*^, Silver J*. High-resolution intravital imaging reveals that blood derived macrophages but not resident microglia facilitate secondary axonal dieback in traumatic spinal cord injury. Experimental Neurology 2014; 254:109-120 (Featured as Journal Cover; *Shared Senior Author; ^Communicating PI).

Scrimieri, F, Askew D, Corn DJ, Eid S, Bobanga ID, Bjelac JA, Tsao ML, Othman YS, Wang SG, Huang AY. Murine Leukemia Virus Envelope Gp70 is a Shared Biomarker for High-sensitivity Detection and Quantification of Murine Tumors. OncoImmunology 2014; 2(11): e26889.

Bodas P, Huang A, ORiordan MA, Sedor JR, Dell KM. The prevalence of Hypertension and Abnormal Kidney Function in Children with Sickle Cell Disease - a Cross Sectional Review. BMC Nephrol. 2013; 14(1):237.

Bobanga ID, Petrosiute A, Huang AY. Chemokines as Cancer Vaccine Adjuvants. Vaccines 2013; 1:444-463.

Barkauskas DS*, Evans TA*, Myers J, Petrosiute A, Silver J, Huang AY. Extravascular CX3CR1+ Cells Extend Intravascular Dendritic Processes intoIntact Central Nervous System Vessel Lumen. Microscopy & Microanalysis 2013; 19(4):778-90.

Myers J, Barkauskas DS, Huang AY. Dynamic imaging of marrow-resident granulocytes interacting with human mesenchymal stem cell upon systemic lipopolysaccharide challenge. Stem Cell International. 2013; 2013:656839.
(Highlighted by Global Medical Discovery... read the article)

Huang AY, Haining WN, Barkauskas DS, Myers J, Petrosiute A, Garrett AP, Singh K, Cooke K, Kean LS. Viewing transplantation immunology through today's lens: new models, new imaging, and new insights. Biol. Blood Marrow Transplant. 2013; 19(1 Suppl):S44-51

Mandl JN, Liou R, Klauschen F, Vrisekoop N, Monteiro JP, Yates AJ, Huang AY*, Germain RN*. Quantification of lymph node transit times reveals differences in antigen surveillance strategies of naive CD4+ and CD8+ T cells. Proc. Natl. Acad. Sci. USA 2012; doi/10.1073/pnas.1211717109 (*co-senior author)

Huang AY, Myers JT, Barkauskas D, Howell SJ, Oleinick NL, McCormick TS, Cooper KD, Baron ED, Lam M. Cutaneous penetration of the topically applied photosensitizer Pc4 as detected by intravital 2-photon laser scanning microscopy. Phtodiag. Photodyn. Ther. 2012; 9(3):225-231.

Liou HLR, Myers JT, Barkauskas DS, Huang AY. Intravital imaging of the mouse popliteal lymph node. J. Vis. Exp. 2012; Feb 8 (60); pii: 3720. doi:10.3791/3720
 
Lathia JD, Gallagher J, Myers JT, Li M, Vasanji A, McLendon RE, Hjelmeland AB, Huang AY, Rich JN. In vivo evidence for tumor propagation by glioblastoma cancer stem cells. PLoS One. 2011; 6(9):e24807. Epub 2011 Sep 22.
 
Pareek, TK, Lam E, Zheng X, Askew D, Kulkarni AB, Chance MR, Huang AY, Cooke KR, Letterio JJ. Cyclin-dependent kinase 5 activity is required for T cell activation and induciton of experimental autoimmune encephalomyelitis. J. Exp. Med. 2010; 207(11):2507-2519.
 
Simmons DP, Canaday DH, Liu Y, Li Q, Huang A, Boom WH, Harding CV. Mycobacgterium tuberculosis and TLR2 agonists inhibit induction of type I IFN and class I MHC antigen cross processing by TLR9. J. Immunol. 2010; 185(4):2405-2415.
 
Myers J, Huang Y, Wei L, Yan Q, Huang A, Zhou L. Fucose-deficient hematopoietic stem cells have decreases self-renewal and aberrant marrow niche occupancy. Transfusion 2010; 50(12):2660-2669.
 
Huang AY. Bulging glands? Blame it on B cells. Blood. 2010; 115(23):4624- 4626.
 
Germain RN, Bajenoff M, Castellino F, Chieppa M, Egen JG, Huang AYC, Ishii M, Koo LY, Qi H. Making friends in out-of-the-way places: how cells of the immune system get together and how they conduct their business as revealed by intravital imaging. Immunological Reviews 2008; 221:163-181

Bajenoff M, Egen JG, Qi H, Huang AY, Castellino F, Germain RN. Highways, byways and breadcrumbs: directing lymphocyte traffic in the lymph node. Trends Immunol. 2007, 28(8): 346-352.

Guarda G, Hons M, Soriano SF, Huang AY, Polley R, Martin-Fontecha A, Stein JV, Germain RN, Lanzavecchia A, Sallusto F. L-selectin- CCR7- effector and memory CD8+ T cells enter reactive lymph nodes and kill dendritic cells. Nat. Immunol. 2007, 8(7):743-52.
 
Huang AY. Watching Immune Cells in Action. Biology of Blood and Marrow Transplantation. 2007, 13:111-114.
 
Chieppa M, Rescigno M, Huang AY, Germain RN. Dynamic imaging of dendritic cell extension into the small bowel lumen in response to epithelial cell TCL engagement. J Exp Med. 2006, 203:2841-52.
 
Qi H, Egen JG, Huang AY, Germain RN. Extrafollicular activation of lymph node B cells by antigen-bearing dendritic cells. Science 2006, 312-1672-76.
 
Castellino F*, Huang AY*, Altan-Bonnet G, Stoll S, Scheinecker C, Germain RN. Chemokines enhance immunity by guiding naive CD8+ T cells to sites of CD4+ T cell-dendritic cell interaction. Nature 2006, 440:890-95 (*shared first authorship).
 
Bajenoff M, Breart B, Huang AY, Qi H, Cazareth J, Braud VM, Germain RN, Glaichenhaus N. Natureal killer cell behavior in lymph nodes revealed by static and real-time imaing. J Exp Med. 2006, 203:619-31.
 
Germain RN, Castellino F, Chieppa M, Egen JG, Huang AY, Koo LY, Qi H. An extended vision for dynamic high-resolution intravita immune imaging. Semin Immunol. 2005, 17:431-41.
 
Huang AY, Qi H, Germain RN. Illuminating the landscape of in vivo immunity: insights from dynamic in situ imaging of secondary lymphoid tissues. Immunity 2004, 21:331-339.
 
[for a complete list of publications, please see ABOUT US page]

 


Huang Lab NEWS...
Dawn of a new era in cancer therapy: Immunotherapy




December 12, 2014

Congratulations to Dr. Agne Petrosiute
for receiving a $10,000 Core Utilization Grant from CTSC for her project to identify targets of Cdk5 enzymatic activity in CNS tumors.





December 4, 2014

The Huang Lab is very grateful to receive another year of funding support from the Pediatric Cancer Research Foundation (PCRF) in the amount of $25,000 to for our ongoing research into pulmonary metastasis of Osteosarcoma.

December 4, 2014

We are honored to help launch the Keira Kilbane Foundation. Please support this most worthy cause.
   


November 6, 2014

The Huang Lab has been awarde
d one of 20 infrastructure grants by the St. Baldrick's Foundation in the amount of $50,000. This fund supports personnel in the lab charged with building a patient-derived xenograft farm for Pediatric and AYA cancer specimens in an effort to expand our research in immunotherapy for childhood and AYA cancers. Read CWRU News Release.


2014

ReadAgne's blog on Medulloblastoma on St. Baldrick's Foundation website.




September 23, 2014

Congratulations to Dr. Agne Petrosiute for receiving a $250,000 Hyundai Hope-on-Wheels Hope Grant at a Hand Print Ceremony today at UH Atrium. Dr. Petrosiute also attended a Pediatric Oncology Think Tank Summit at Washington D.C. last week. Congratulations, Agne!


(Watch local news coverage of the event)

  


September 15, 2014

Congratulations to Fred Allen for being awarded a 3-year NRSA F31 Fellowship Award from NCI/NIH on his proposed study, "Inflammatory chemokine CCL3 in the tumor microenvironment leads to enhanced antitutmor immune development in the draining lymph node." Way to go, Fred!


September 13, 2014

We are grateful to receive a scholarship support for fellow-initiated research in childhood cancer from the Samuel Szabo Foundation. Please help support this great Foundation. We look forward to developing a great relationship with the Foundation and to help furthering the great cause! The recipient of the Fellowship Grant will be announced soon.


September 12, 2014

We are almost halfway through our September Fundraising for Childhood Cancer through Alex's Lemonade Stand Foundation's Million Mile R
un Initiative. Team "Run, Alex! Run!" is raising the miles and dollars to stand in solidarity with children and families battling childhood and adolescent cancer. Every dollar donated through "Run, Alex! Run!" team will come back doubled directly to Rainbow Pediatric Research, and every mile run, walked or biked will be matched by a $1 donation from Northwestern Mutual. Starting mid-night September 15 through 6am September 16 (30 hours), every dollar donated to team, "Run, Alex! Run!" will be matched $ for $ by Volvo. The funds will be raised to help establish the Keira Kilbane Research Fund in memory of Princess Keira.
        

August 21, 2014

Congratulations to Dr. Leland Metheny for receiving a $10,000 Core Utilization Grant from CTSC for his project "Pre-Clinical Model Using Pluristem Administration for Delayed Engraftment after Heatopoietic Cell Transplant." This project is co-mentored by Dr. Hillard Lazarus.


August, 2014

The Huang Lab is once again getting ready for the Million Mile Run (MMR) in support of Alex's Lemonade Stand Foundation. In September, team "Run, Alex! Run!" will be raising awareness and research funds in support of childhood cancer research in partnership with the Alex's Lemonade Stand Foundation. Every $$ you give through Team "Run, Alex! Run!" will double (2X) and come back directly to the Huang Lab. You can: 1) join the team (www.alexslemonade.org/mypage/1116964); 2) Text to donate $10 (text "lemonade E1116964" to 89544); 3) Participate in our 5K Run on Saturday, September 6 at 10am on MLK Drive near University Circle; 4) Have fun at the Scavenger Hunt, Saturday September 27 at 3pm-6pm; 5) Join a Raffle Drawing on Saturday September 27 with a First Prize a iPad mini.

Click here for more information! We are counting on your support!


August 12, 2014

Read an article featured in St. Baldrick's FoundationNewsletter as Dr. Petrosiute discusses research on immunotherapy for Medulloblastoma.


July 1, 2014

Another academic year has come and gone.... and we say our fond good-byes to Dr. Francesca Scrimieri, Dr. Iuli Bobaga, Dr. Teresa Evans and Matt Tsao. We will miss all of you. Come back to visit often!










June 24, 2014

Congratulations to Dr. Agne Petrosiute for her promotion to the rank of Assistant Professor in the Department of Pediatrics at Case Western Reserve University.


June 11, 2014

The entire Huang Lab family was recognized by the University Hospitals for their many accomplishments through the dedication of the endowed Theresia G. & Stuart F. Kline Family Foundation Chair of Pediatric Oncology to Dr. Huang.

          


May, 2014

Congratulations to Leland Metheny, MD for winning the Best Abstract Award  at the Department of Medicine Science Day, CWRU / UH.

May, 2014

Congratulations to Francesca Scrimieri for being named a finalist of the 2014 Paola Campese Award for Research in Cancer, Italian Scientists and Scholars of North American Foundation. Winner will be announced later in the fall.


May 13, 2014

Congratulations to Iuliana Bobanga, MD for wining first place oral presentation at the Cleveland Surgical Society meeting.


May 8, 2014

Congratulations to Iuliana Bobanga, MD for winning first place oral presentation at the ACS Ohio Chapter meeting


April 18, 2014

Thanks to everyone's support and effort, the Huang Lab / UH / Rainbow Head Shaving Fundraiser for St. Baldrick's Foundation was a phenomenal success, raising more than $41,000 with 100+ heads shaved. Read a blog on St. Baldrick's Foundation website describing the involvement of Huang Lab's annual fundraising effort!


April 16, 2014

Congratulations to Dr. Scrimieri for winning the best oral presentation award at the annual Musculoskeletal Research Symposium. Way to go, Francesca!




April 14, 2014

The Huang Lab was recognized by the Alex's Lemonade Stand Foundation for being one of the top 100 fundraising team in 2013. Thanks to the effort of all members of the "Run, Alex! Run!" team during last September's Million Mile Run (MMR). The Huang Lab raised close to $10,000 in the month of September!

             

April 14, 2014

Congratulations to Dr. Agne Petrosiute for receiving the 2014-2015 Hyundai Hope-on-Wheels Hope Award in the amount of $250,000 (1/1/2015-12/31/2016). Official announcements will be made on September 23, 2014 at 10am at the UH Atrium.
                                              


April 2014

Latest publication from Huang Lab (Evans et al. Exp. Neurol. 2014; 254:109-120) was featured as the cover of the Journal's April 2014 issue. Congratulations, Teresa.







March 20, 2014

Congratulations to Dixon Dorand for receiving the Trainee Poster Award and the Minority Scientist Travel Award at the upcoming AAI meeting in Pittsburgh in May 2014.






March 17, 2014

Congratulations to Deb Barkauskas for successfully defending her PhD thesis. Congratulations, Dr. Barkauskas!



March 14, 2014

Members of the Huang Lab had yet another strong showing at this year's St. Baldrick's Head Shaving event held at the UH Rainbow Babies & Children's Hospital. Team Rainbow raised almost $25,000, and UH Rainbow site has raised more than $38,000 with more than 100 heads shaved. You can still donate to this great cause by visiting here: SBF Team Rainbow

February 12, 2014

Congratulations to Teresa Evans for successfully defending her PhD thesis. Congraulations, Dr. Evans!




February 6, 2014

Congratulations to Dr. Iuli Bobanga, MD for being selected as 1 of 10 best abstract submissions among more than a 1000 posters at this week's 2014 American Surgical Congress in San Diego, CA. She was chosen for oral presentation at this prestigious meeting. Way to go, Iuli!

                  



February 4, 2014

Dr. Huang describes one of the projects funded by the Pediatric Cancer Research Foundation (PCRF).
 





December 3, 2013

The Huang lab hosted members of the Steven G. AYA Cancer Research Fund. We are so grateful for the generosity, support, and partnership of the Steven G. AYA Fund throughout this past year. Read the blog and support this worthy organization in our shared vision of curing childhood and adolescent cancer!




October 29, 2013

Congratulations to Jay for having his recent Stem Cell International article featured by BitPlane Inc. Read the article.


October 16, 2013

The Huang participated in the second Appreciative Inquiry project in partnership with the Weatherhead School of Management. Click to see the slideshow of the AI project. Click here to see the interactive slideshow of the first AI project held in the fall of 2012.

October, 2013

Congratulations to David Askew for winning the Poster Presentation Award at the 7th Annual Immunology Training Program Annual Retreat held at the Cleveland Clinic Lerner Research Institute on September 28, 2013.



October, 2013

Congratulations to Dixon Dorand who has just been named, "Bert & Iris Wolstein Research Scholar in Pediatric Oncology" with a funding support totaling $25,000.




October 4, 2013

The Huang Lab had a phenomenal month in partnering with Alex's Lemonade Stand Foundation to raise awareness for Childhood Cancer by participating in ALSF's Million Mile Run Initiative. Team "Run, Alex! Run" raised more than $9000 for childhood cancer research, and has collectively run or walked more than 900 miles! Great Job everyone! See the YouTube video featuring Jay Myers, Deb Barkauskas and Alex, along with countless other warriors around the country united for the same great cause!


September 30, 2013

The Huang Lab presented data as the lead-off speaker for the 21st Annual Cancer Immunotherapy Meeting during the 60th Anniversary of the Cancer Research Institute (CRI) at the Grand Hyatt in New York




September 24, 2013

The Huang Lab received 2013 Hyundai "Hope-on-Wheels" Hope Award at a ceremony at UH Atrium. Thanks to Hyundai for their support of Pediatric Cancer Research.



September 13, 2013

The Huang Lab is grateful to receive the support of the Steven G. AYA Cancer Research Fund. Read the article featuring Dr. David Askew and summer student, Robert Purgert.



September 10, 2013

Congratulations to Jay for being selected by the Midwest Blood Club to receive the best abstract / poster presentation award at their annual meeting to be held on September 19, 2013 in Cincinnati. Congratulations, Jay!



July 26, 2013

The Huang Lab has joined the great cause of "Go the Distance for Kids with Cancer!" by participating "the Million Mile Run (or Walk) in September" project sponsored by Alex's Lemonade Stand Foundation. Visit our participation website, sign up to join our team and raise funds and awareness for childhood cancer research! You caneither join the team and run/walk to raise funds, or donate to one of the team members... either way, you can be part of this great movement while getting yourself in shape! Visit our fundraising website for team "Run, Alex! Run!".
                                                      

July 19, 2013

Congratulations to Dr. Agne Petrosiute, MD for being awarded a St. Baldrick's Fellowship Extension Award!Read the Announcement.


July 12, 2013

Congratulations to Dr. Iuliana Bobanga, MD for winning a poster presentation prize at the Case Comprehensive Cancer Center Retreat on July 12, 2013.


May, 2013

Congratulations to the following individual for receiving Summer Fellowship support:

Tim Welliver, Ph.D. - CWRU SOM student - St. Baldrick's Summer Fellow
Nathan Teich - CWRU SOM student - St. Baldrick's Summer Fellow
Robert Purgert - Miami University undergrad - Steven G. AYA Summer Fellow



May, 2013

Congratulations to Iuliana Bobanga, MD for winning first place at the annual meeting of the Ohio Chapter of American Surgical Society on May 3rd.


May, 2013

We are grateful to receive the support and partnership of The Littlest Heroes Vs. Cancer Foundation. Please check out their website and give them your full support!



April, 2013

The Huang lab has just received a 2-year, $250,000 grant from Hyundai "Hope-on-Wheels" Hope Award to study the role of Cdk's in ICN1-induced T-ALL. Hand print ceremony will occur in the Fall at the University Hospitals.
More details to come. Stay tuned.

April, 2013

Congratulations to Fred Allen for being awarded a Minority Scientist Travel Award at the upcoming American Association of Immunologists (AAI) Annual Meeting in Hawaii



March 31, 2013

Huang Lab and Team Rainbow Head Shaving Fundraising Effort on behalf of St. Baldrick's Foundation was featured on the Steven G. AYA Cancer Research Fund website.

March 18, 2013

A special ceremony took place in the Rainbow Performance Area on Monday morning as local event organizers, volunteers and shavees of the 2013 St. Baldrick's Foundation Fundraising Event Cleveland Chapter came together to celebrate and welcome Kathleen Ruddy, CEO of St. Baldrick's Foundation. Watch and read about this event as reported on Channel 5 News.


March 14, 2013

Member of the Huang Lab had another great showing this year at the annual St. Baldrick's Foundation Head Shaving Event at Rainbow Babies & Children's Hospital. Deb Barkauskas has de-throned Alex this year as the top fundraiser on Team Rainbow, and more money is pouring in. Please consider contributing to this most worthy cause in fueling research funding for Childhood Cancer Research. See Fox8 New coverage of this event.

February 26, 2013

Huang lab members have started the annual ritual of getting heads shaved to raise funds in support of St. Baldrick's Foundation, a terrific foundation which supports Pediatric Hematology-Oncology Research. Please check out Team Rainbow and support this worthy cause.

The Head-Shaving Date is Thursday, March 14th from 10:30am to 12:30pm in the Performance Area of Rainbow Babies & Children's Hospital.



January 26, 2013

Huang lab members were honored at the annual Steven G. AYA Research Fund fundraiser dinner. Drs. David Askew, Iuliana Bobanga, Agne Petrosiute, Alex Huang and Mrs. Deborah Barkauskas were in attendance to help support this worthy cause.


November 13, 2012

Dr. Huang spoke at the annual meeting of the Gabrielle's Angel Foundation in New York's Central Park Loeb Boathouse. Check out the video where Dr. Huang (0:52) and other speakers at the symposium spoke of the importance of the funding from GAF in supporting many of our ongoing research initiatives.

November 1, 2012

Congratulations to Dr. David Askew who was named the 2012 Recipient of the Steven G. AYA Cancer Research Scholarship. The entire Huang Lab is grateful for the support and partnership of the Steven G. AYA Cancer Research Fund! Read more about Dr. Askew's Award and please be sure to support the Steven G. AYA Cancer Researh Fund.  Thank you, Steven, Angie and Harry!


October, 2012

Congratulations to Dixon Dorand for being named recipient of the CWRU ITP T32 Training Grant Recipient for his study into antigen processing and presentation pathways of CNS Tumor-associated antigens. Congratulations Dixon.



 September 1, 2012


Congratulations to Fred Allen for receiving a two-year NIH NCI Diversity Supplement Grant to study intranodal immune cell migration in metastatic colon tumors. Congratulations, Fred!



September 12, 2012

Congratulations to Dr. Agne Petrosiute, who received the 2012 Hyundai Hope-on-Wheel Program Research Award in the amount of $75,000. Congratulations, Agne!
 

Watch local Cleveland Fox8 News and 19 Action News Coverage of the event and Agne's speech...

July 6, 2012
 
Read the latest press release regarding ALSF Innovator Award in Case Daily and WKYC

May 2012

We are fortunate to be visited by Harry and Angie Giallourakis from the Steven G AYA Cancer Research Fund on May 18th. We are so grateful for their passion and dedication to finding a cure for AYA cancer. Read the blog about the Huang Lab on their website.

May 2012

Huang Lab have just received a 2-year Innovation Award from the Alex's Lemonade Stand Foundation in the amount of $200,000. This grant is a collaborative project among Drs. Huang, Petrosiute and Dr. Nicole Steinmetz (BME, CWRU) aimed at enhancing immune surveillance in brain tumors.



Fracesca Scrimieri, Ph.D.
April 2012
 
Dr. Francesca Scrimieri just received appointment to the Orthopedic Department's T32 Training Program for her ongoing work in osteosarcoma.




March 2012
Member of the Huang Lab participated in the St. Baldrick's Foundation's annual head-shaving fundraising event as part of the Rainbow Babies & Children's Team. Team Rainbow had over 33 shaves, raising more than $27,000 (second top team in Cleveland). Dr. Huang raised $4900, placing him on top-ten list of individual fund-raisers from the City of Cleveland. To celebrate Cleveland's 10th anniversary in participating in this most worthy cause, Team Rainbow hosted its first-ever hair-shaving event in the Atrium of University Hospitals on March 9th.



September 2011
Deborah Sim Barkauskas
 
 
Deborah Barkauskas received appointment to the Biomedical Engineering Department's T32 Training Program for her ongoing work in CNS imaging.

 

August 2011Deborah Sim Barkauskas

Congratulations to Deborah Barkauskas for winning best poster presentation at the 2011 Annual International Microscopy & Microanalysis Meeting in Nashville, TN.



 July 2011Agne Petrosiute

Congratulations to Dr. Agne Petrosiute, MD for being awarded the FRAP Career Development Award. This $40,000 award is given to one senior fellow-junior faculty each year in the Department of Pediatrics in support and recognition of his/her accomplishment in research.
 
 

June 2011
Youmna Othman, M.D.
Congratulations to Youmna Othman, MD for being chosen as a recipient of the St. Baldrick's Fellow Scholarship through a competitive national grant review process for her proposal to monitor T cell ALL infiltration in the CNS through the Blood-Brain Barrier in a spontaneous murine leukemia model. This award is for a 2-year period in the amount exceeding $155,000.
 

June 2011

Dr. Alex Huang has received an additional $230,000 grant from the St. Baldrick's Foundation for the laboratory's effort to define immune surveillance in pediatric sarcomas and other cancers.
 

April 2011

Congratulations to Deborah Barkauskas for being named the 2011 Distinguished Scholar Award in the upcoming Microscopy & Microanalysis 2011 meeting in Nashville, TN for her paper entitled, Monitoring Immune Cell Infiltration in the Brain with Intravital Two-Photon Microscopy. She will receive compensation to attend the annual meeting in August, and will present her research finding in T cell recruitment in EAE as a poster.

March 2011

The Huang lab has another spectacular year of fund-raising on behalf of the St. Baldrick's Foundation. Dr. Huang, Jay Myers, and Jennifer Tsai were part of the Rainbow Babies & Children's Hospital Team which raised a record $23,000+. Dr. Huang was among the top 10 personal fundraisers in the city of Cleveland, with more than $4700.

March 2011

Congratulations to Jennifer Tsai, CWRU SOM for being named a St. Baldrick's Summer Fellow for her work in characterizing antigen presenting cell populations in the CNS of EAE mosue. The award is for a total of $5000 for one year.



Our lab / shipping address:

 

Wolstein Research Building, Room 6402

2103 Cornell Road

Cleveland, OH 44106-7288

(216) 368-0015

 

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2103 Cornell Road, Cleveland, OH 44106
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